We walked from Grand Place to the City 2 Shopping Mall in 30 minutes. It was an easy walk with many photo stops and just gazing at the surroundings.
On arrival at City 2 there was a modern shopping complex with department stores and most likely a hundred or more speciality shops, restaurants, cafes etc. It was similar to any other shopping centre in a modern city. We had lunch at one of the cafes and my wife purchased some cosmetics from one of the speciality shops. She said prices were much lower than at home.
If you are looking for some ordinary High Street shopping with brands like H&M, Zara, Etam, C&A and many others, Rue Neuve/Nieuwstraat is it. My only wonder is how there can be three perfume stores of the same chain and so on but as long as they're happy, I'm happy :))) The street ends with the famous Inno department store and the City2 shopping mall which houses two of my favourites in the form of Fnac - a French based book and media chain - and a French chain with outdoor things, maps and educational toys.