The Six Eyed Sand Spider rarely comes into contact with people and even when it does, it generally never bites. Further, like most spiders, it does not always inject venom with every bite, nor, even when it does, does it necessarily inject a large amount.
The six-eyed sand spider () is a medium-sized with body measuring 8 to 15 mm and legs spanning up to 50 mm,:p.24 found in deserts and other sandy places in southern . It is a member of the family; close relatives may be found in both Africa and in , and its near cousins, the (), are found worldwide. Due to its flattened stance and laterigrade legs, it is also sometimes known as the six-eyed crab spider. Bites by Sicarius to humans are uncommon; there are no proven cases and only two suspected cases where the culprit was never identified. Sicarius bites have been experimentally shown as lethal to rabbits within 5 to 12 hours.:p.25 The genus name is Latin for 'murderer', from , a curved dagger. The species was named after .
The venom of this spider’s bite is said to be the most dangerous on record. Over 38,000 species of six-eyed sand spider have been identified, however, because of their great hiding ability, it is believed that about 200,000 species exist.